| Gene Information | |
|---|---|
| Gene Name | CIITA |
| Organism | Homo sapiens (Human) |
| Gene Length | 1130 |
| Protein Names | MHC class II transactivator (CIITA) (EC 2.3.1.-) (EC 2.7.11.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000179583 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P33076 |
| Gene Card | CIITA |
| Uniprot ID | P33076 |
| Pfam | PF13516; PF05729 |
| In ASD | no |
| Allosteric Prediction | no (-0.152778524) |
| Ortholog in Animals | Alpaca_ CIITA ( ortholog_one2one ) Dog_ CIITA ( ortholog_one2one ) GuineaPig_ CIITA ( ortholog_one2one ) Macaque_ CIITA ( ortholog_one2one ) Mouse_ Ciita ( ortholog_one2one ) Pig_ CIITA ( ortholog_one2one ) Rat_ Ciita ( ortholog_one2one ) Rabbit_ CIITA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NLRP9, NLRC5, NLRP14, NLRP7, NLRP4, NOD1, NLRP8, NLRP10, NLRP3, NLRP5, NLRP6, NLRP11, NLRP2, PYDC2, NLRC3, NLRX1, NLRP12, NLRP13, NLRP1, NOD2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2229317 rs8046121 rs4774 rs2229319 rs13330686 rs13336804 rs7197779 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:23007646}. Nucleus, PML body {ECO:0000269|PubMed:23007646}. Note=Recruited to PML body by PML. |
| Mouse PG classification | NA |
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