| Gene Information | |
|---|---|
| Gene Name | CACNG2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Voltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit) (Transmembrane AMPAR regulatory protein gamma-2) (TARP gamma-2) |
| Target Name | voltage-dependent calcium channel |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000166862 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y698 |
| Gene Card | CACNG2 |
| Uniprot ID | Q9Y698 |
| Pfam | PF00822 |
| In ASD | yes |
| Allosteric Prediction | yes (0.823529357) |
| Ortholog in Animals | Alpaca_ CACNG2 ( ortholog_one2one ) Dog_ CACNG2 ( ortholog_one2one ) GuineaPig_ CACNG2 ( ortholog_one2one ) Macaque_ CACNG2 ( ortholog_one2one ) Mouse_ Cacng2 ( ortholog_one2one ) Pig_ CACNG2 ( ortholog_one2one ) Rat_ Cacng2 ( ortholog_one2one ) Rabbit_ CACNG2 ( ortholog_one2one ) |
| Ohnologs | CACNG3, CACNG4 |
| Paralogs | CACNG7, CACNG5, CACNG3, CACNG8, CACNG4 |
| Tissue | NA |
| Tissue Specificity | Brain. |
| Pharmacological Animal Models | 0.102410(Chimpanzee);0.268507(Mouse);NULL(Rat);0.357195(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 6DLZ (EM 3.90A ) 6DM0 (EM 4.40A ) 6DM1 (EM 4.20A ) 6O9G (EM 4.80A ) 6TNO (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. Synapse, synaptosome {ECO:0000250|UniProtKB:Q71RJ2}. |
| Mouse PG classification | NA |
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