| Gene Information | |
|---|---|
| Gene Name | H2BC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 127 |
| Protein Names | Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000146047 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96A08 |
| Gene Card | H2BC1 |
| Uniprot ID | Q96A08 |
| Pfam | PF00125 |
| In ASD | no |
| Allosteric Prediction | no (-0.039250584) |
| Ortholog in Animals | Alpaca_ H2BC1 ( ortholog_one2one ) Dog_ H2BC2 ( ortholog_one2many ) GuineaPig_ H2BC1 ( ortholog_one2one ) Macaque_ H2BC1 ( ortholog_one2one ) Mouse_ H2bc1 ( ortholog_one2one ) Pig_ H2BC1 ( ortholog_one2one ) Rat_ H2bc1 ( ortholog_one2one ) |
| Ohnologs | H2BC21 |
| Paralogs | H2BK1, H2BU1, H2BC21, H2BC17, H2BC12L, H2BC11, H2BC12, H2BC18, H2BC10, H2BC15, H2BW2, H2BC4, H2BC5, H2BC7, H2BW1, H2BC3, H2BC6, H2BC8, H2BC13, H2BC9, H2BC14 |
| Tissue | testis |
| Tissue Specificity | Mainly expressed in testis, and the corresponding protein is also present in mature sperm (at protein level). Also found in some fat cells. {ECO:0000269|PubMed:12213818, ECO:0000269|PubMed:21249133}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001133(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3WKJ (X-ray 2.80A ) 5GSU (X-ray 3.10A ) 5GT3 (X-ray 2.91A ) 6BIY (X-ray 2.05A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:P70696}. Chromosome {ECO:0000250|UniProtKB:P70696}. |
| Mouse PG classification | NA |
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