| Gene Information | |
|---|---|
| Gene Name | PLCB4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1175 |
| Protein Names | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000101333 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15147 |
| Gene Card | PLCB4 |
| Uniprot ID | Q15147 |
| Pfam | PF00168; PF06631; PF09279; PF17787; PF00388; PF00387 |
| In ASD | no |
| Allosteric Prediction | yes (0.663333558) |
| Ortholog in Animals | Alpaca_ PLCB4 ( ortholog_one2one ) Dog_ PLCB4 ( ortholog_one2one ) GuineaPig_ PLCB4 ( ortholog_one2one ) Macaque_ PLCB4 ( ortholog_one2one ) Mouse_ Plcb4 ( ortholog_one2one ) Pig_ PLCB4 ( ortholog_one2one ) Rat_ Plcb4 ( ortholog_one2one ) Rabbit_ PLCB4 ( ortholog_one2one ) |
| Ohnologs | PLCB2, PLCB3 |
| Paralogs | PLCG2, PLCD3, PLCB3, PLCE1, PLCG1, PLCB1, PLCD4, PLCD1, PLCB2, PLCL2, PLCH1, PLCL1, PLCZ1, PLCH2 |
| Tissue | NA |
| Tissue Specificity | Preferentially expressed in the retina. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6077510 rs387907179 rs397514482 rs397514481 rs397514480 rs397514483 rs6118603 |
| Subcellular location [CC] | NA |
| Mouse PG classification | LPG |
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