| Gene Information | |
|---|---|
| Gene Name | AFAP1L2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 818 |
| Protein Names | Actin filament-associated protein 1-like 2 (AFAP1-like protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000169129 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N4X5 |
| Gene Card | AFAP1L2 |
| Uniprot ID | Q8N4X5 |
| Pfam | PF00169 |
| In ASD | no |
| Allosteric Prediction | no (-0.237372457) |
| Ortholog in Animals | Alpaca_ AFAP1L2 ( ortholog_one2one ) Dog_ AFAP1L2 ( ortholog_one2one ) GuineaPig_ AFAP1L2 ( ortholog_one2one ) Macaque_ AFAP1L2 ( ortholog_one2one ) Mouse_ Afap1l2 ( ortholog_one2one ) Pig_ AFAP1L2 ( ortholog_one2one ) Rat_ Afap1l2 ( ortholog_one2one ) Rabbit_ AFAP1L2 ( ortholog_one2one ) |
| Ohnologs | AFAP1L1, AFAP1 |
| Paralogs | AFAP1L1, AFAP1 |
| Tissue | NA |
| Tissue Specificity | Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas. {ECO:0000269|PubMed:17412687}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2COF (NMR - ) |
| DBSNP | rs11196689 rs7075067 rs2781806 rs11599051 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17412687}. |
| Mouse PG classification | NA |
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