| Gene Information | |
|---|---|
| Gene Name | ADRB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 408 |
| Protein Names | Beta-3 adrenergic receptor (Beta-3 adrenoreceptor) (Beta-3 adrenoceptor) |
| Target Name | beta adrenergic receptor |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000188778 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P13945 |
| Gene Card | ADRB3 |
| Uniprot ID | P13945 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.558712134) |
| Ortholog in Animals | Alpaca_ ADRB3 ( ortholog_one2one ) Dog_ ADRB3 ( ortholog_one2one ) Macaque_ ADRB3 ( ortholog_one2one ) Mouse_ Adrb3 ( ortholog_one2one ) Pig_ ADRB3 ( ortholog_one2one ) Rat_ Adrb3 ( ortholog_one2one ) Rabbit_ ADRB3 ( ortholog_one2one ) |
| Ohnologs | ADRB1, HRH2, ADRB2 |
| Paralogs | OR56A4, ADRA2A, ADRB2, ADRA2B, OR56A1, OR56A3, OR56A5, DRD2, ADRA1B, ADRA1D, OR5T2, OR5T3, OR5T1, ADRA1A, GPR101, ADRB1, OR13F1, ADRA2C |
| Tissue | NA |
| Tissue Specificity | Expressed mainly in adipose tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4994 rs28364012 rs4995 rs36031925 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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