| Gene Information | |
|---|---|
| Gene Name | FFAR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 346 |
| Protein Names | Free fatty acid receptor 3 (G-protein coupled receptor 41) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000185897 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14843 |
| Gene Card | FFAR3 |
| Uniprot ID | O14843 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000024185) |
| Ortholog in Animals | Dog_ FFAR3 ( ortholog_one2many ) Mouse_ Ffar3 ( ortholog_one2many ) Rat_ Ffar3 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | GPR42, FFAR2, P2RY2, P2RY4, OXGR1, P2RY1, SUCNR1, P2RY6, GPR82, GPR31, FFAR1, HCAR3, HCAR1, HCAR2, OXER1 |
| Tissue | NA |
| Tissue Specificity | Highest level in adipose tissue, and lower expression across all tissues tested. Expressed in sympathetic ganglia. {ECO:0000269|PubMed:12496283, ECO:0000269|PubMed:21518883}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs382771 rs1359000742 rs1415955990 rs1395869674 rs1170582382 rs201080710 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:18801738}; Multi-pass membrane protein {ECO:0000269|PubMed:18801738}. |
| Mouse PG classification | NA |
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