Gene Information
Gene NameGZMK
OrganismHomo sapiens (Human)
Gene Length264
Protein NamesGranzyme K (EC 3.4.21.-) (Fragmentin-3) (Granzyme-3) (NK-tryptase-2) (NK-Tryp-2)
Target NameNA
Target TypeNA
Gene Age132 ( ENSG00000113088 )
Evolutionary StageEumetazoa
AlphaFoldDBP49863
Gene CardGZMK
Uniprot IDP49863
PfamPF00089
In ASDno
Allosteric Predictionno (-0.32875298)
Ortholog in AnimalsAlpaca_ GZMK ( ortholog_one2one )
Dog_ GZMK ( ortholog_one2one )
GuineaPig_ GZMK ( ortholog_one2one )
Macaque_ GZMK ( ortholog_one2one )
Mouse_ Gzmk ( ortholog_one2one )
Pig_ GZMK ( ortholog_one2one )
Rat_ Gzmk ( ortholog_one2one )
Rabbit_ GZMK ( ortholog_one2one )
OhnologsNA
ParalogsGZMA, MST1, PIK3IP1, HABP2, HGF
TissueNA
Tissue SpecificityExpressed in lung, spleen, thymus and peripheral blood leukocytes.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1MZA  (X-ray  2.23A  1MZD  (X-ray  2.90A 
DBSNP NA 
Subcellular location [CC]Secreted. Cytoplasmic granule.
Mouse PG classificationNA
click here to return to the previous page