| Gene Information | |
|---|---|
| Gene Name | GZF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 711 |
| Protein Names | GDNF-inducible zinc finger protein 1 (Zinc finger and BTB domain-containing protein 23) (Zinc finger protein 336) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000125812 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9H116 |
| Gene Card | GZF1 |
| Uniprot ID | Q9H116 |
| Pfam | PF00651; PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-1.220653239) |
| Ortholog in Animals | Alpaca_ GZF1 ( ortholog_one2one ) Dog_ GZF1 ( ortholog_one2one ) GuineaPig_ GZF1 ( ortholog_one2one ) Macaque_ GZF1 ( ortholog_one2one ) Mouse_ Gzf1 ( ortholog_one2one ) Pig_ GZF1 ( ortholog_one2one ) Rat_ Gzf1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZBTB17, ZNF527, PRDM2, ZNF467, ZNF530, ZNF784, ZNF416, ZNF746, ZNF547, ZKSCAN7, ZNF407, ZNF646, ZNF852, ZNF408, ZNF774, ZNF572, ZNF426, ZNF398, ZNF333, ZNF223, ZNF222, ZNF287, ZNF625, ZNF644, ZNF233, PRDM4, ZNF697, ZNF319, ZNF34, ZNF285, WIZ, ZNF507, ZNF136, ZNF592, ZBTB41, ZNF214, ZNF777, ZNF417, ZNF587, ZFP57, ZNF776, ZNF687, MYNN, ZNF627, ZNF707, ZNF17, ZNF670, ZNF230, ZNF155, ZNF768 |
| Tissue | NA |
| Tissue Specificity | Expressed in adult brain, heart, skeletal muscle, kidney and liver. Also detected in fetal brain and kidney, and at lower levels in fetal lung and liver. {ECO:0000269|PubMed:14522971}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3810574 rs6048760 rs6048760 rs6048760 rs6114068 rs6048766 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:14522971}. Nucleus, nucleoplasm {ECO:0000269|PubMed:14522971, ECO:0000269|PubMed:17674968}. Nucleus, nucleolus {ECO:0000269|PubMed:17674968}. Note=Nuclear localization depends upon NCL. {ECO:0000269|PubMed:17674968}. |
| Mouse PG classification | NA |
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