| Gene Information | |
|---|---|
| Gene Name | GUF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 669 |
| Protein Names | Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000151806 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8N442 |
| Gene Card | GUF1 |
| Uniprot ID | Q8N442 |
| Pfam | PF00679; PF00009; PF03144; PF06421 |
| In ASD | no |
| Allosteric Prediction | no (-0.925803456) |
| Ortholog in Animals | Alpaca_ GUF1 ( ortholog_one2one ) Dog_ GUF1 ( ortholog_one2one ) GuineaPig_ GUF1 ( ortholog_one2one ) Macaque_ GUF1 ( ortholog_one2one ) Mouse_ Guf1 ( ortholog_one2one ) Pig_ GUF1 ( ortholog_one2one ) Rat_ Guf1 ( ortholog_one2one ) Rabbit_ GUF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EFTUD2, EIF2S3, EIF2S3B, GTPBP1, EIF5B, MTIF2, EEF2, EFL1, GSPT2, EEFSEC, EEF1A1, EEF1A2, HBS1L, GTPBP2, GFM2, GFM1, GSPT1, TUFM |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001162(Rat);0.019672(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6447368 rs10470742 rs879255631 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000255|HAMAP-Rule:MF_03137}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03137}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03137}. |
| Mouse PG classification | NA |
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