| Gene Information | |
|---|---|
| Gene Name | WNT7A |
| Organism | Homo sapiens (Human) |
| Gene Length | 349 |
| Protein Names | Protein Wnt-7a |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000154764 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O00755 |
| Gene Card | WNT7A |
| Uniprot ID | O00755 |
| Pfam | PF00110 |
| In ASD | no |
| Allosteric Prediction | no (-0.392934059) |
| Ortholog in Animals | Alpaca_ WNT7A ( ortholog_one2one ) Dog_ WNT7A ( ortholog_one2one ) GuineaPig_ WNT7A ( ortholog_one2one ) Macaque_ WNT7A ( ortholog_one2one ) Mouse_ Wnt7a ( ortholog_one2one ) Pig_ WNT7A ( ortholog_one2one ) Rat_ Wnt7a ( ortholog_one2one ) Rabbit_ WNT7A ( ortholog_one2one ) |
| Ohnologs | WNT2, WNT3, WNT7B, WNT5A |
| Paralogs | WNT5A, WNT6, WNT3, WNT4, WNT2B, WNT2, WNT9B, WNT16, WNT8B, WNT11, WNT3A, WNT7B, WNT5B, WNT10A, WNT9A, WNT10B, WNT1, WNT8A |
| Tissue | NA |
| Tissue Specificity | Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4UZQ (X-ray 1.50A ) |
| DBSNP | rs397514666 rs879255548 rs104893832 rs397514643 rs104893835 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000305}. Secreted {ECO:0000269|PubMed:26902720}. |
| Mouse PG classification | HPG |
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