Gene Information
Gene NameGUC1A3
OrganismHomo sapiens (Human)
Gene Length690
Protein NamesGuanylate cyclase soluble subunit alpha-1 (GCS-alpha-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit alpha-3) (GCS-alpha-3) (Soluble guanylate cyclase large subunit)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ02108
Gene CardGUCY1A1
Uniprot IDQ02108
PfamPF00211; PF07701
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityDetected in brain cortex and lung (at protein level). {ECO:0000269|PubMed:1352257}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.004323(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3UVJ  (X-ray  2.08A  4NI2  (X-ray  1.90A  6JT0  (EM  4.00A  6JT1  (EM  3.90A  6JT2  (EM  3.80A  7D9R  (EM  3.30A  7D9S  (EM  3.40A  7D9T  (EM  4.10A  7D9U  (EM  3.80A 
DBSNP rs2170646 
Subcellular location [CC]Cytoplasm {ECO:0000305}.
Mouse PG classificationNA
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