| Gene Information | |
|---|---|
| Gene Name | CMIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 773 |
| Protein Names | C-Maf-inducing protein (c-Mip) (Truncated c-Maf-inducing protein) (Tc-Mip) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000153815 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IY22 |
| Gene Card | CMIP |
| Uniprot ID | Q8IY22 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.117067742) |
| Ortholog in Animals | Alpaca_ CMIP ( ortholog_one2one ) Dog_ CMIP ( ortholog_one2one ) GuineaPig_ CMIP ( ortholog_one2one ) Macaque_ CMIP ( ortholog_one2one ) Mouse_ Cmip ( ortholog_one2one ) Pig_ CMIP ( ortholog_one2one ) Rat_ Cmip ( ortholog_one2one ) Rabbit_ CMIP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver. Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturation and differentiation in thymus and fetal liver. {ECO:0000269|PubMed:12939343}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12939343}. Cytoplasm {ECO:0000269|PubMed:12939343}. Note=Isoform 2 is translocated to the nucleus and is specifically recruited during minimal change nephrotic syndrome (MCNS) (PubMed:12939343) (PubMed:15616553). Detected in nuclear and cytoplasmic compartments during MCNS relapse (PubMed:12939343) (PubMed:15616553). Expressed in cytoplasm only during MCNS remission and absent in normal patients (PubMed:12939343). {ECO:0000269|PubMed:12939343, ECO:0000269|PubMed:15616553}. |
| Mouse PG classification | NA |
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