| Gene Information | |
|---|---|
| Gene Name | CAV3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 151 |
| Protein Names | Caveolin-3 (M-caveolin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000182533 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P56539 |
| Gene Card | CAV3 |
| Uniprot ID | P56539 |
| Pfam | PF01146 |
| In ASD | no |
| Allosteric Prediction | yes (0.279601754) |
| Ortholog in Animals | Alpaca_ CAV3 ( ortholog_one2one ) Dog_ CAV3 ( ortholog_one2one ) GuineaPig_ CAV3 ( ortholog_one2one ) Macaque_ CAV3 ( ortholog_one2one ) Mouse_ Cav3 ( ortholog_one2one ) Pig_ CAV3 ( ortholog_one2one ) Rat_ Cav3 ( ortholog_one2one ) Rabbit_ CAV3 ( ortholog_one2one ) |
| Ohnologs | CAV2, CAV1 |
| Paralogs | CAV1, CAV2 |
| Tissue | heart, skeletal.muscle, artery, tongue |
| Tissue Specificity | Expressed predominantly in muscle. {ECO:0000269|PubMed:9545514}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121909281 rs116840778 rs116840782 rs116840786 rs1008642 rs116840788 rs116840789 rs116840773 rs116840794 rs72546667 rs116840795 rs116840796 rs199476332 rs121909280 rs116840776 rs72546668 rs121909282 rs104893715 rs28936685 rs28936686 rs104893714 rs116840805 rs116840777 rs104893713 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250|UniProtKB:P51638}; Peripheral membrane protein {ECO:0000250}. Membrane, caveola {ECO:0000250|UniProtKB:P51637}; Peripheral membrane protein {ECO:0000250}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P51637}. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity). {ECO:0000250}. |
| Mouse PG classification | HPG |
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