Gene Information
Gene NameGTF2H1
OrganismHomo sapiens (Human)
Gene Length548
Protein NamesGeneral transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000110768 )
3 ( ENSG00000288114 )
Evolutionary StageEukaryota
AlphaFoldDBP32780
Gene CardGTF2H1
Uniprot IDP32780
PfamPF03909; PF08567
In ASDno
Allosteric Predictionno (-0.087943238)
Ortholog in AnimalsAlpaca_ GTF2H1 ( ortholog_one2one )
Dog_ GTF2H1 ( ortholog_one2one )
GuineaPig_ GTF2H1 ( ortholog_one2one )
Macaque_ GTF2H1 ( ortholog_one2one )
Mouse_ Gtf2h1 ( ortholog_one2one )
Pig_ GTF2H1 ( ortholog_one2one )
Rat_ Gtf2h1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.065217(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1PFJ  (NMR  -  )  2DII  (NMR  -  )  2RNR  (NMR  -  )  2RUK  (NMR  -  )  2RVB  (NMR  -  )  5GOW  (NMR  -  )  5XV8  (NMR  -  )  6NMI  (EM  3.70A  )  6O9L  (EM  7.20A  )  6O9M  (EM  4.40A  )  7AD8  (EM  3.50A  )  7BUL  (NMR  -  )  7EGB  (EM  3.30A  )  7EGC  (EM  3.90A  )  7ENA  (EM  4.07A  )  7ENC  (EM  4.13A  )  7LBM  (EM  4.80A  )  7NVR  (EM  4.50A  )  7NVW  (EM  4.30A  )  7NVX  (EM  3.90A  )  7NVY  (EM  7.30A  )  7NVZ  (EM  7.20A  )  7NW0  (EM  6.60A  ) 
DBSNP rs4150603  rs4150636  rs4150665 
Subcellular location [CC]Nucleus.
Mouse PG classificationNA
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