| Gene Information | |
|---|---|
| Gene Name | GTF2E1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 439 |
| Protein Names | General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000153767 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P29083 |
| Gene Card | GTF2E1 |
| Uniprot ID | P29083 |
| Pfam | PF08271; PF11521; PF02002 |
| In ASD | no |
| Allosteric Prediction | no (-0.452783001) |
| Ortholog in Animals | Alpaca_ GTF2E1 ( ortholog_one2one ) Dog_ GTF2E1 ( ortholog_one2one ) GuineaPig_ GTF2E1 ( ortholog_one2one ) Macaque_ GTF2E1 ( ortholog_one2one ) Mouse_ Gtf2e1 ( ortholog_one2one ) Pig_ GTF2E1 ( ortholog_one2one ) Rat_ Gtf2e1 ( ortholog_one2one ) Rabbit_ GTF2E1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.599172(Rat);0.254340(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1VD4 (NMR - ) 2JTX (NMR - ) 2RNQ (NMR - ) 2RNR (NMR - ) 5GPY (X-ray 2.10A ) 5IY6 (EM 7.20A ) 5IY7 (EM 8.60A ) 5IY8 (EM 7.90A ) 5IY9 (EM 6.30A ) 5IYA (EM 5.40A ) 5IYB (EM 3.90A ) 5IYC (EM 3.90A ) 5IYD (EM 3.90A ) 6O9L (EM 7.20A ) 7EG9 (EM 3.70A ) 7EGA (EM 4.10A ) 7EGB (EM 3.30A ) 7EGC (EM 3.90A ) 7ENA (EM 4.07A ) 7ENC (EM 4.13A ) 7LBM (EM 4.80A ) 7NVR (EM 4.50A ) 7NVS (EM 2.80A ) 7NVT (EM 2.90A ) 7NVU (EM 2.50A ) 7NVV (EM 2.90A ) 7NVW (EM 4.30A ) 7NVX (EM 3.90A ) 7NVY (EM 7.30A ) 7NVZ (EM 7.20A ) 7NW0 (EM 6.60A ) |
| DBSNP | rs3732401 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:1956398, ECO:0000269|PubMed:7651391}. |
| Mouse PG classification | NA |
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