| Gene Information | |
|---|---|
| Gene Name | TMEM8B |
| Organism | Homo sapiens (Human) |
| Gene Length | 472 |
| Protein Names | Transmembrane protein 8B (Nasopharyngeal carcinoma-associated gene 6 protein) (Protein NAG-5) (Protein NGX6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000137103 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | A6NDV4 |
| Gene Card | TMEM8B |
| Uniprot ID | A6NDV4 |
| Pfam | PF12036 |
| In ASD | no |
| Allosteric Prediction | no (-1.413759531) |
| Ortholog in Animals | Alpaca_ TMEM8B ( ortholog_one2one ) Dog_ TMEM8B ( ortholog_one2one ) GuineaPig_ TMEM8B ( ortholog_one2one ) Macaque_ TMEM8B ( ortholog_one2one ) Mouse_ Tmem8b ( ortholog_one2one ) Pig_ TMEM8B ( ortholog_one2one ) Rat_ Tmem8b ( ortholog_one2one ) Rabbit_ TMEM8B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PGAP6, MYMK |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 2]: Cell membrane {ECO:0000269|PubMed:17641538}; Multi-pass membrane protein {ECO:0000269|PubMed:17641538}. Cytoplasm {ECO:0000269|PubMed:17641538}. Nucleus {ECO:0000269|PubMed:17641538}. Mitochondrion {ECO:0000269|PubMed:17641538}. Endoplasmic reticulum {ECO:0000269|PubMed:17641538}. Note=Also detected in mitochondrion and endoplasmic reticulum (PubMed:17641538). |
| Mouse PG classification | NA |
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