| Gene Information | |
|---|---|
| Gene Name | GSTT2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | Glutathione S-transferase theta-2B (EC 2.5.1.18) (Glutathione S-transferase theta-2) (GST class-theta-2) |
| Target Name | glutathione s-transferases (cytosolic) |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000133433 ) 3 ( ENSG00000278695 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P0CG30 |
| Gene Card | GSTT2B |
| Uniprot ID | P0CG30 |
| Pfam | PF00043; PF02798 |
| In ASD | no |
| Allosteric Prediction | no (-0.546389637) |
| Ortholog in Animals | Mouse_ Gstt2 ( ortholog_one2many ) Rat_ Gstt2 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | CLIC2, GSTZ1, GSTO2, GDAP1L1, CLIC3, GSTT4, CLIC4, CLIC1, EEF1G, GDAP1, GSTO1, CLIC6, CLIC5, GSTT2 |
| Tissue | adrenal.gland |
| Tissue Specificity | Expressed at low levels in liver. In lung, expressed at low levels in ciliated bronchiolar cells, alveolar macrophages and alveolar type II cells. {ECO:0000269|PubMed:8761485}. |
| Pharmacological Animal Models | 0.029547(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1LJR (X-ray 3.20A ) 2LJR (X-ray 3.20A ) 3LJR (X-ray 3.30A ) 4MPG (X-ray 1.95A ) |
| DBSNP | rs1622002 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:1417752}. |
| Mouse PG classification | NA |
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