| Gene Information | |
|---|---|
| Gene Name | SULT1C2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 302 |
| Protein Names | Sulfotransferase 1C4 (ST1C4) (EC 2.8.2.1) (Sulfotransferase 1C2) (SULT1C#2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000198203 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75897 |
| Gene Card | SULT1C4 |
| Uniprot ID | O75897 |
| Pfam | PF00685 |
| In ASD | no |
| Allosteric Prediction | yes (0.224881527) |
| Ortholog in Animals | Alpaca_ SULT1C2 ( ortholog_one2one ) Dog_ SULT1C2 ( ortholog_one2one ) GuineaPig_ SULT1C2 ( ortholog_one2one ) Macaque_ SULT1C2 ( ortholog_one2one ) Mouse_ Sult1c2 ( ortholog_one2one ) Pig_ SULT1C2 ( ortholog_one2one ) Rat_ Sult1c2a ( ortholog_one2many ) Rat_ RGD1559960 ( ortholog_one2many ) Rat_ Sult1c2 ( ortholog_one2many ) Rabbit_ SULT1C2 ( ortholog_one2one ) |
| Ohnologs | SULT2B1, SULT2A1, SULT1E1, SULT4A1, SULT1B1 |
| Paralogs | SULT2B1, SULT1B1, SULT1C3, SULT6B1, SULT1C4, SULT2A1, SULT1A2, SULT1A1, SULT1A4, SULT1A3, SULT1E1, SULT4A1 |
| Tissue | stomach, kidney, cortex.of.kidney, thyroid |
| Tissue Specificity | Expressed at high levels in fetal lung and kidney and at low levels in fetal heart, adult kidney, ovary and spinal chord. {ECO:0000269|PubMed:9852044}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2AD1 (X-ray 2.00A ) 2GWH (X-ray 1.80A ) |
| DBSNP | rs1402467 rs41322445 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:28222028}. |
| Mouse PG classification | NA |
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