| Gene Information | |
|---|---|
| Gene Name | GSTS |
| Organism | Homo sapiens (Human) |
| Gene Length | 199 |
| Protein Names | Hematopoietic prostaglandin D synthase (H-PGDS) (EC 5.3.99.2) (GST class-sigma) (Glutathione S-transferase) (EC 2.5.1.18) (Glutathione-dependent PGD synthase) (Glutathione-requiring prostaglandin D synthase) (Prostaglandin-H2 D-isomerase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O60760 |
| Gene Card | HPGDS |
| Uniprot ID | O60760 |
| Pfam | PF14497; PF02798 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver. {ECO:0000269|PubMed:10824118, ECO:0000269|PubMed:11672424, ECO:0000269|PubMed:9353279, ECO:0000269|PubMed:9425264}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1IYH (X-ray 1.70A ) 1IYI (X-ray 1.80A ) 1V40 (X-ray 1.90A ) 2CVD (X-ray 1.45A ) 2VCQ (X-ray 1.95A ) 2VCW (X-ray 1.95A ) 2VCX (X-ray 2.10A ) 2VCZ (X-ray 1.95A ) 2VD0 (X-ray 2.20A ) 2VD1 (X-ray 2.25A ) 3EE2 (X-ray 1.91A ) 3KXO (X-ray 2.10A ) 3VI5 (X-ray 2.00A ) 3VI7 (X-ray 2.00A ) 4EC0 (X-ray 1.85A ) 4EDY (X-ray 1.72A ) 4EDZ (X-ray 2.00A ) 4EE0 (X-ray 1.75A ) 5AIS (X-ray 1.85A ) 5AIV (X-ray 2.04A ) 5AIX (X-ray 2.10A ) 5YWE (X-ray 1.68A ) 5YWX (X-ray 1.74A ) 5YX1 (X-ray 1.39A ) 6N4E (X-ray 1.65A ) 6W58 (X-ray 2.40A ) 6W8H (X-ray 1.97A ) 6ZTC (X-ray 1.84A ) 7JR6 (X-ray 1.88A ) 7JR8 (X-ray 1.13A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9353279}. |
| Mouse PG classification | NA |
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