| Gene Information | |
|---|---|
| Gene Name | GSTO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 243 |
| Protein Names | Glutathione S-transferase omega-2 (GSTO-2) (EC 2.5.1.18) (Glutathione S-transferase omega 2-2) (GSTO 2-2) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) |
| Target Name | glutathione s-transferase omega-2 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000065621 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H4Y5 |
| Gene Card | GSTO2 |
| Uniprot ID | Q9H4Y5 |
| Pfam | PF13417 |
| In ASD | no |
| Allosteric Prediction | no (-0.339150192) |
| Ortholog in Animals | Alpaca_ GSTO2 ( ortholog_one2one ) Dog_ GSTO2 ( ortholog_one2one ) GuineaPig_ GSTO2 ( ortholog_one2one ) Macaque_ GSTO2 ( ortholog_one2one ) Mouse_ Gsto2 ( ortholog_one2one ) Pig_ GSTO2 ( ortholog_one2one ) Rat_ Gsto2 ( ortholog_one2one ) Rabbit_ GSTO2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CLIC2, GSTZ1, GDAP1L1, CLIC3, GSTT4, CLIC4, GSTT2, GSTT2B, CLIC1, EEF1G, GDAP1, GSTO1, CLIC6, CLIC5 |
| Tissue | NA |
| Tissue Specificity | Expressed in a range of tissues, including the liver, kidney, skeletal muscle and prostate. Strongest expression in the testis. {ECO:0000269|PubMed:12618591}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3Q18 (X-ray 1.70A ) 3Q19 (X-ray 1.90A ) 3QAG (X-ray 2.00A ) |
| DBSNP | rs45582439 rs156697 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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