Gene Information
Gene NameGSTM4
OrganismHomo sapiens (Human)
Gene Length218
Protein NamesGlutathione S-transferase Mu 4 (EC 2.5.1.18) (GST class-mu 4) (GST-Mu2) (GSTM4-4) (Leukotriene C4 synthase GSTM4) (EC 4.4.1.20)
Target Nameglutathione s-transferases (cytosolic)
Target TypeNA
Gene Age987 ( ENSG00000168765 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ03013
Gene CardGSTM4
Uniprot IDQ03013
PfamPF14497; PF02798
In ASDno
Allosteric Predictionno (-0.316211302)
Ortholog in AnimalsAlpaca_ GSTM4 ( ortholog_one2one )
Mouse_ Gstm4 ( ortholog_one2one )
Rat_ Gstm4 ( ortholog_one2one )
OhnologsNA
ParalogsGSTP1, GSTM1, GSTM3, GSTA5, GSTA4, GSTM2, GSTM5, GSTA1, GSTA2, HPGDS, GSTA3
TissueNA
Tissue SpecificityExpressed in a wide variety of tissues.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4GTU  (X-ray  3.30A 
DBSNP rs3211190  rs17838158  rs112611763  rs112330158  rs200675176  rs149370166 
Subcellular location [CC]Cytoplasm {ECO:0000305|PubMed:8373352}.
Mouse PG classificationNA
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