| Gene Information | |
|---|---|
| Gene Name | RBFOX3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 312 |
| Protein Names | RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Neuronal nuclei antigen) (NeuN antigen) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000167281 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | A6NFN3 |
| Gene Card | RBFOX3 |
| Uniprot ID | A6NFN3 |
| Pfam | PF12414; PF00076 |
| In ASD | no |
| Allosteric Prediction | yes (0.086388019) |
| Ortholog in Animals | Alpaca_ RBFOX3 ( ortholog_one2one ) Dog_ RBFOX3 ( ortholog_one2one ) GuineaPig_ RBFOX3 ( ortholog_one2one ) Macaque_ RBFOX3 ( ortholog_one2one ) Mouse_ Rbfox3 ( ortholog_one2one ) Pig_ RBFOX3 ( ortholog_one2one ) Rat_ Rbfox3 ( ortholog_one2one ) |
| Ohnologs | RBFOX2, RBFOX1 |
| Paralogs | RBFOX1, RBFOX2 |
| Tissue | brain, endometrium, prostate, urinary.bladder, cerebellar.hemisphere, cerebellum |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:24215932}. Cytoplasm {ECO:0000269|PubMed:24215932}. Note=Largely restricted to neuronal nuclei. However, significant cytoplasmic localization in neurons from brains from HIV-infected individuals with cognitive impairment. {ECO:0000269|PubMed:24215932}. |
| Mouse PG classification | NA |
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