| Gene Information | |
|---|---|
| Gene Name | GSTM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 218 |
| Protein Names | Glutathione S-transferase Mu 1 (EC 2.5.1.18) (GST HB subunit 4) (GST class-mu 1) (GSTM1-1) (GSTM1a-1a) (GSTM1b-1b) (GTH4) |
| Target Name | glutathione s-transferases (cytosolic) |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000134184 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P09488 |
| Gene Card | GSTM1 |
| Uniprot ID | P09488 |
| Pfam | PF14497; PF02798 |
| In ASD | no |
| Allosteric Prediction | yes (0.295016997) |
| Ortholog in Animals | Alpaca_ GSTM1 ( ortholog_one2one ) GuineaPig_ GSTM1 ( ortholog_one2one ) Mouse_ Gstm6 ( ortholog_one2many ) Mouse_ Gstm2 ( ortholog_one2many ) Mouse_ Gstm3 ( ortholog_one2many ) Mouse_ Gstm1 ( ortholog_one2many ) Rat_ Gstm1 ( ortholog_one2many ) Rat_ AC097845.1 ( ortholog_one2many ) Rat_ Gstm6l ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | GSTP1, GSTM3, GSTA5, GSTA4, GSTM2, GSTM5, GSTM4, GSTA1, GSTA2, HPGDS, GSTA3 |
| Tissue | NA |
| Tissue Specificity | Liver (at protein level). {ECO:0000269|PubMed:7822249}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1GTU (X-ray 2.68A ) 1XW6 (X-ray 1.90A ) 1XWK (X-ray 2.30A ) 1YJ6 (X-ray 2.50A ) 2F3M (X-ray 2.70A ) 7BEU (X-ray 1.59A ) |
| DBSNP | rs1065411 rs449856 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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