| Gene Information | |
|---|---|
| Gene Name | GSTA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 222 |
| Protein Names | Glutathione S-transferase A4 (EC 2.5.1.18) (GST class-alpha member 4) (Glutathione S-transferase A4-4) |
| Target Name | glutathione s-transferase a4 |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000170899 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O15217 |
| Gene Card | GSTA4 |
| Uniprot ID | O15217 |
| Pfam | PF14497; PF02798 |
| In ASD | no |
| Allosteric Prediction | no (-0.79092545) |
| Ortholog in Animals | Alpaca_ GSTA4 ( ortholog_one2one ) Dog_ GSTA4 ( ortholog_one2many ) GuineaPig_ GSTA4 ( ortholog_one2one ) Macaque_ GSTA4 ( ortholog_one2one ) Pig_ GSTA4 ( ortholog_one2one ) Rabbit_ GSTA4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GSTP1, GSTM1, GSTM3, GSTA5, GSTM2, GSTM5, GSTM4, GSTA1, GSTA2, HPGDS, GSTA3 |
| Tissue | NA |
| Tissue Specificity | Expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1GUL (X-ray 2.70A ) 1GUM (X-ray 3.00A ) 3IK7 (X-ray 1.97A ) |
| DBSNP | rs45551133 rs4147617 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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