Gene Information
Gene NameGSC2
OrganismHomo sapiens (Human)
Gene Length205
Protein NamesHomeobox protein goosecoid-2 (GSC-2) (Homeobox protein goosecoid-like) (GSC-L)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000063515 )
Evolutionary StageEukaryota
AlphaFoldDBO15499
Gene CardGSC2
Uniprot IDO15499
PfamPF00046
In ASDno
Allosteric Predictionno (-0.770794819)
Ortholog in AnimalsAlpaca_ GSC2 ( ortholog_one2one )
Dog_ GSC2 ( ortholog_one2one )
GuineaPig_ GSC2 ( ortholog_one2one )
Macaque_ GSC2 ( ortholog_one2one )
Mouse_ Gsc2 ( ortholog_one2one )
Pig_ GSC2 ( ortholog_one2one )
Rat_ Gsc2 ( ortholog_one2one )
OhnologsGSC
ParalogsARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1
TissueNA
Tissue SpecificityDetected in adult testis and pituitary, and in 9-10 week fetal tissue (thorax). Probably expressed in other tissues at low levels.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34341950 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Mouse PG classificationNA
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