| Gene Information | |
|---|---|
| Gene Name | GRXCR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 290 |
| Protein Names | Glutaredoxin domain-containing cysteine-rich protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000215203 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | A8MXD5 |
| Gene Card | GRXCR1 |
| Uniprot ID | A8MXD5 |
| Pfam | PF00462 |
| In ASD | no |
| Allosteric Prediction | no (-0.524943005) |
| Ortholog in Animals | Alpaca_ GRXCR1 ( ortholog_one2one ) Dog_ GRXCR1 ( ortholog_one2one ) GuineaPig_ GRXCR1 ( ortholog_one2one ) Macaque_ GRXCR1 ( ortholog_one2one ) Mouse_ Grxcr1 ( ortholog_one2one ) Pig_ GRXCR1 ( ortholog_one2one ) Rat_ Grxcr1 ( ortholog_one2one ) Rabbit_ GRXCR1 ( ortholog_one2one ) |
| Ohnologs | GRXCR2 |
| Paralogs | GLRX2, GRXCR2 |
| Tissue | NA |
| Tissue Specificity | Expressed at low levels in adult lung, brain and duodenum with moderate levels in testis. Highly expressed in fetal cochlea. {ECO:0000269|PubMed:20137778}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs78136490 rs367784906 rs727505186 rs370551174 rs113203706 rs267606856 rs770874273 |
| Subcellular location [CC] | Cell projection, stereocilium {ECO:0000250}. Cell projection, microvillus {ECO:0000250}. Cell projection, kinocilium {ECO:0000250}. Note=In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia. {ECO:0000250}. |
| Mouse PG classification | NA |
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