Gene Information
Gene NameECSIT
OrganismHomo sapiens (Human)
Gene Length431
Protein NamesEvolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000130159 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ9BQ95
Gene CardECSIT
Uniprot IDQ9BQ95
PfamPF06239; PF14784
In ASDno
Allosteric Predictionno (-0.032938467)
Ortholog in AnimalsAlpaca_ ECSIT ( ortholog_one2one )
Dog_ ECSIT ( ortholog_one2one )
GuineaPig_ ECSIT ( ortholog_one2one )
Macaque_ ECSIT ( ortholog_one2one )
Mouse_ Ecsit ( ortholog_one2one )
Pig_ ECSIT ( ortholog_one2one )
Rat_ Ecsit ( ortholog_one2one )
Rabbit_ ECSIT ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.003543(Rat);0.063415(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34803265  rs2302971 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:17344420}. Nucleus {ECO:0000269|PubMed:17344420}. Mitochondrion {ECO:0000269|PubMed:17344420}.
Mouse PG classificationNA
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