| Gene Information | |
|---|---|
| Gene Name | GRSF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 480 |
| Protein Names | G-rich sequence factor 1 (GRSF-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000132463 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q12849 |
| Gene Card | GRSF1 |
| Uniprot ID | Q12849 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-1.450820504) |
| Ortholog in Animals | Alpaca_ GRSF1 ( ortholog_one2one ) Dog_ GRSF1 ( ortholog_one2one ) GuineaPig_ GRSF1 ( ortholog_one2one ) Macaque_ GRSF1 ( ortholog_one2one ) Mouse_ Grsf1 ( ortholog_one2one ) Pig_ GRSF1 ( ortholog_one2one ) Rat_ Grsf1 ( ortholog_one2one ) Rabbit_ GRSF1 ( ortholog_one2one ) |
| Ohnologs | HNRNPH2, HNRNPH1, HNRNPF |
| Paralogs | HNRNPF, RBM12B, HNRNPH3, ESRP1, ESRP2, RBM12, HNRNPH1, HNRNPH2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LMI (NMR - ) 4QU6 (X-ray 1.75A ) 4QU7 (X-ray 2.50A ) |
| DBSNP | rs17854012 |
| Subcellular location [CC] | [Isoform 1]: Mitochondrion matrix {ECO:0000269|PubMed:23473033, ECO:0000269|PubMed:23473034, ECO:0000269|PubMed:25683715, ECO:0000269|PubMed:29967381}. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. {ECO:0000269|PubMed:23473033, ECO:0000269|PubMed:23473034, ECO:0000269|PubMed:25683715}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:23473034}. |
| Mouse PG classification | NA |
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