| Gene Information | |
|---|---|
| Gene Name | GRP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 400 |
| Protein Names | Cytohesin-3 (ARF nucleotide-binding site opener 3) (Protein ARNO3) (General receptor of phosphoinositides 1) (Grp1) (PH, SEC7 and coiled-coil domain-containing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43739 |
| Gene Card | CYTH3 |
| Uniprot ID | O43739 |
| Pfam | PF00169; PF01369 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Almost absent from liver, thymus and peripheral blood lymphocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4KAX (X-ray 1.85A ) 6U3E (EM 53.00A ) 6U3G (EM 53.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol. Cell membrane {ECO:0000250|UniProtKB:O08967}; Peripheral membrane protein {ECO:0000250|UniProtKB:O08967}. Cell junction, adherens junction {ECO:0000250|UniProtKB:O08967}. Cell junction, tight junction {ECO:0000250|UniProtKB:O08967}. Note=Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate. {ECO:0000250|UniProtKB:O08967}. |
| Mouse PG classification | NA |
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