| Gene Information | |
|---|---|
| Gene Name | GRP |
| Organism | Homo sapiens (Human) |
| Gene Length | 148 |
| Protein Names | Gastrin-releasing peptide (GRP) [Cleaved into: Neuromedin-C (GRP-10) (GRP18-27)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000134443 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P07492 |
| Gene Card | GRP |
| Uniprot ID | P07492 |
| Pfam | PF02044 |
| In ASD | no |
| Allosteric Prediction | no (-0.012546753) |
| Ortholog in Animals | Alpaca_ GRP ( ortholog_one2one ) Dog_ GRP ( ortholog_one2one ) GuineaPig_ GRP ( ortholog_one2one ) Macaque_ GRP ( ortholog_one2one ) Mouse_ Grp ( ortholog_one2one ) Pig_ GRP ( ortholog_one2one ) Rat_ Grp ( ortholog_one2one ) Rabbit_ GRP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NMB |
| Tissue | brain |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2N0B (NMR - ) 2N0C (NMR - ) 2N0D (NMR - ) 2N0E (NMR - ) 2N0F (NMR - ) 2N0G (NMR - ) 2N0H (NMR - ) |
| DBSNP | rs1062557 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:3211139}. Cytoplasmic vesicle, secretory vesicle lumen {ECO:0000250|UniProtKB:Q863C3}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q8R1I2}. Note=In neurons of the retrotrapezoid nucleus/parafacial respiratory group, expressed on neuron projections which project into the pre-Botzinger complex. {ECO:0000250|UniProtKB:Q8R1I2}. |
| Mouse PG classification | NA |
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