| Gene Information | |
|---|---|
| Gene Name | ORMDL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 153 |
| Protein Names | ORM1-like protein 2 (Adoplin-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000123353 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q53FV1 |
| Gene Card | ORMDL2 |
| Uniprot ID | Q53FV1 |
| Pfam | PF04061 |
| In ASD | no |
| Allosteric Prediction | no (-0.946031897) |
| Ortholog in Animals | Alpaca_ ORMDL2 ( ortholog_one2one ) Dog_ ORMDL2 ( ortholog_one2many ) GuineaPig_ ORMDL2 ( ortholog_one2one ) Macaque_ ORMDL2 ( ortholog_one2one ) Mouse_ Ormdl2 ( ortholog_one2one ) Pig_ ORMDL2 ( ortholog_one2one ) Rat_ Ormdl2 ( ortholog_one2many ) Rabbit_ ORMDL2 ( ortholog_one2one ) |
| Ohnologs | ORMDL3, ORMDL1 |
| Paralogs | ORMDL1, ORMDL3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus. {ECO:0000269|PubMed:12093374}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12093374}; Multi-pass membrane protein {ECO:0000269|PubMed:12093374}. |
| Mouse PG classification | NA |
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