| Gene Information | |
|---|---|
| Gene Name | CYTIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 359 |
| Protein Names | Cytohesin-interacting protein (Cytohesin binder and regulator) (CYBR) (Cytohesin-associated scaffolding protein) (CASP) (Cytohesin-binding protein HE) (Cbp HE) (Pleckstrin homology Sec7 and coiled-coil domains-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000115165 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O60759 |
| Gene Card | CYTIP |
| Uniprot ID | O60759 |
| Pfam | PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.994090215) |
| Ortholog in Animals | Alpaca_ CYTIP ( ortholog_one2one ) Dog_ CYTIP ( ortholog_one2one ) GuineaPig_ CYTIP ( ortholog_one2one ) Macaque_ CYTIP ( ortholog_one2one ) Mouse_ Cytip ( ortholog_one2one ) Pig_ CYTIP ( ortholog_one2one ) Rat_ Cytip ( ortholog_one2one ) Rabbit_ CYTIP ( ortholog_one2one ) |
| Ohnologs | TAMALIN |
| Paralogs | TAMALIN |
| Tissue | whole.blood |
| Tissue Specificity | Expressed in lymph nodes, thymus, spleen, lung, peripheral blood leukocytes and bone marrow. {ECO:0000269|PubMed:11867758, ECO:0000269|PubMed:12606567}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2Z17 (X-ray 2.70A ) |
| DBSNP | rs1042038 rs2229345 |
| Subcellular location [CC] | Cytoplasm. Early endosome. Note=Recruited from the cytosol to endosomes by SNX27. |
| Mouse PG classification | NA |
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