| Gene Information | |
|---|---|
| Gene Name | GRK7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 553 |
| Protein Names | Rhodopsin kinase GRK7 (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000114124 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WTQ7 |
| Gene Card | GRK7 |
| Uniprot ID | Q8WTQ7 |
| Pfam | PF00069; PF00615 |
| In ASD | no |
| Allosteric Prediction | yes (0.814413354) |
| Ortholog in Animals | Alpaca_ GRK7 ( ortholog_one2one ) Dog_ GRK7 ( ortholog_one2one ) GuineaPig_ GRK7 ( ortholog_one2one ) Macaque_ GRK7 ( ortholog_one2one ) Pig_ GRK7 ( ortholog_one2one ) Rabbit_ GRK7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RSKR, GRK5, GRK1, GRK4, GRK3, GRK6, GRK2 |
| Tissue | NA |
| Tissue Specificity | Retinal cones, outer and inner segments. {ECO:0000269|PubMed:11754336, ECO:0000269|PubMed:18803695}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34429284 rs56070798 rs34769632 rs35318124 rs55707760 rs56019094 rs35566288 rs55824414 rs56076641 rs36009541 rs33928105 rs36004830 |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:Q8WMV0}; Lipid-anchor {ECO:0000250|UniProtKB:Q8WMV0}. |
| Mouse PG classification | NA |
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