| Gene Information | |
|---|---|
| Gene Name | GRK3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 688 |
| Protein Names | Beta-adrenergic receptor kinase 2 (Beta-ARK-2) (EC 2.7.11.15) (G-protein-coupled receptor kinase 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100077 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P35626 |
| Gene Card | GRK3 |
| Uniprot ID | P35626 |
| Pfam | PF00169; PF00069; PF00615 |
| In ASD | no |
| Allosteric Prediction | no (-0.015628108) |
| Ortholog in Animals | Alpaca_ GRK3 ( ortholog_one2one ) Dog_ GRK3 ( ortholog_one2one ) GuineaPig_ GRK3 ( ortholog_one2one ) Macaque_ GRK3 ( ortholog_one2one ) Mouse_ Grk3 ( ortholog_one2one ) Pig_ GRK3 ( ortholog_one2one ) Rat_ Grk3 ( ortholog_one2one ) Rabbit_ GRK3 ( ortholog_one2one ) |
| Ohnologs | GRK2 |
| Paralogs | RSKR, GRK7, GRK5, GRK1, GRK4, GRK6, GRK2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs55700971 rs55740593 rs2272859 |
| Subcellular location [CC] | Postsynapse {ECO:0000250|UniProtKB:P26819}. Presynapse {ECO:0000250|UniProtKB:P26819}. |
| Mouse PG classification | NA |
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