| Gene Information | |
|---|---|
| Gene Name | TAOK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1001 |
| Protein Names | Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1) |
| Target Name | serine/threonine-protein kinase tao1 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000160551 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7L7X3 |
| Gene Card | TAOK1 |
| Uniprot ID | Q7L7X3 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.182023519) |
| Ortholog in Animals | Alpaca_ TAOK1 ( ortholog_one2one ) Dog_ TAOK1 ( ortholog_one2one ) GuineaPig_ TAOK1 ( ortholog_one2one ) Macaque_ TAOK1 ( ortholog_one2one ) Mouse_ Taok1 ( ortholog_one2one ) Pig_ TAOK1 ( ortholog_one2one ) Rat_ Taok1 ( ortholog_one2one ) Rabbit_ TAOK1 ( ortholog_one2one ) |
| Ohnologs | TAOK3, TAOK2 |
| Paralogs | PAK5, PAK6, PAK4, SBK2, STK39, MAP4K1, PAK2, PAK1, PAK3, MINK1, TNIK, MAP4K5, SLK, MAP3K14, MAP3K19, STRADB, STK4, MAP3K1, TAOK2, MAP4K3, NRK, STRADA, MAP2K3, STK10, MAP2K6, STK26, TAOK3, MAP3K8, MAP4K2, OXSR1, STK3, NEK4, STK25, STK24, MAP4K4 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle. {ECO:0000269|PubMed:13679851, ECO:0000269|PubMed:9786855}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs2030976698 rs34151057 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:13679851}. |
| Mouse PG classification | NA |
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