| Gene Information | |
|---|---|
| Gene Name | GRIP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1128 |
| Protein Names | Glutamate receptor-interacting protein 1 (GRIP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000155974 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y3R0 |
| Gene Card | GRIP1 |
| Uniprot ID | Q9Y3R0 |
| Pfam | PF00595; PF17820 |
| In ASD | no |
| Allosteric Prediction | no (-0.068657262) |
| Ortholog in Animals | Alpaca_ GRIP1 ( ortholog_one2one ) Dog_ GRIP1 ( ortholog_one2one ) GuineaPig_ GRIP1 ( ortholog_one2one ) Macaque_ GRIP1 ( ortholog_one2one ) Mouse_ Grip1 ( ortholog_one2one ) Pig_ GRIP1 ( ortholog_one2one ) Rat_ Grip1 ( ortholog_one2one ) Rabbit_ GRIP1 ( ortholog_one2one ) |
| Ohnologs | GRIP2 |
| Paralogs | MAGI3, MAGI2, SAV1, MAGIX, GRIP2, MAGI1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2JIL (X-ray 1.50A ) |
| DBSNP | rs17102531 |
| Subcellular location [CC] | Cytoplasmic vesicle {ECO:0000269|PubMed:10197531}. Perikaryon {ECO:0000250|UniProtKB:P97879}. Cell projection, dendrite {ECO:0000250|UniProtKB:P97879}. Cytoplasm {ECO:0000250|UniProtKB:P97879}. Endomembrane system {ECO:0000250|UniProtKB:P97879}; Peripheral membrane protein {ECO:0000250|UniProtKB:P97879}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:P97879}. Postsynaptic density {ECO:0000250|UniProtKB:P97879}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:10197531}; Peripheral membrane protein {ECO:0000250|UniProtKB:P97879}. Note=Membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in postsynaptic plasma membrane and postsynaptic densities. {ECO:0000250|UniProtKB:P97879}. |
| Mouse PG classification | NA |
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