| Gene Information | |
|---|---|
| Gene Name | UNQ339/PRO538/PRO3664 |
| Organism | Homo sapiens (Human) |
| Gene Length | 400 |
| Protein Names | GDNF family receptor alpha-3 (GDNF receptor alpha-3) (GDNFR-alpha-3) (GFR-alpha-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O60609 |
| Gene Card | GFRA3 |
| Uniprot ID | O60609 |
| Pfam | PF02351 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression. Very low or no expression detected in the hematopoietic system. {ECO:0000269|PubMed:9576965}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2GH0 (X-ray 1.92A ) 6Q2S (EM 3.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Lipid-anchor, GPI-anchor. |
| Mouse PG classification | NA |
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