| Gene Information | |
|---|---|
| Gene Name | ACADM |
| Organism | Homo sapiens (Human) |
| Gene Length | 421 |
| Protein Names | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7) (Medium chain acyl-CoA dehydrogenase) (MCADH) |
| Target Name | medium-chain specific acyl-coa dehydrogenase, mitochondrial |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000117054 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P11310 |
| Gene Card | ACADM |
| Uniprot ID | P11310 |
| Pfam | PF00441; PF02770; PF02771 |
| In ASD | no |
| Allosteric Prediction | yes (0.486923448) |
| Ortholog in Animals | Alpaca_ ACADM ( ortholog_one2one ) Dog_ ACADM ( ortholog_one2one ) GuineaPig_ ACADM ( ortholog_one2one ) Macaque_ ACADM ( ortholog_one2one ) Mouse_ Acadm ( ortholog_one2one ) Pig_ ACADM ( ortholog_one2one ) Rat_ Acadm ( ortholog_one2one ) Rabbit_ ACADM ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACOX1, ACAD11, ACAD9, IVD, GCDH, ACOXL, ACAD10, ACADS, ACOX3, ACAD8, ACOX2, ACADVL, ACADSB, ACADL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1EGC (X-ray 2.60A ) 1EGD (X-ray 2.40A ) 1EGE (X-ray 2.75A ) 1T9G (X-ray 2.90A ) 2A1T (X-ray 2.80A ) 4P13 (X-ray 1.73A ) |
| DBSNP | rs398123072 rs121434280 rs398123074 rs875989859 rs121434283 rs875989854 rs121434277 rs121434279 rs121434278 rs200724875 rs121434276 rs121434281 rs121434274 rs121434282 rs747268471 rs786204631 rs77931234 rs1227800781 rs121434275 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:16020546}. |
| Mouse PG classification | NA |
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