| Gene Information | |
|---|---|
| Gene Name | CA14 |
| Organism | Homo sapiens (Human) |
| Gene Length | 337 |
| Protein Names | Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV) |
| Target Name | carbonic anhydrase |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000118298 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9ULX7 |
| Gene Card | CA14 |
| Uniprot ID | Q9ULX7 |
| Pfam | PF00194 |
| In ASD | no |
| Allosteric Prediction | no (-0.450560443) |
| Ortholog in Animals | Alpaca_ CA14 ( ortholog_one2one ) Dog_ CA14 ( ortholog_one2one ) GuineaPig_ CA14 ( ortholog_one2one ) Macaque_ CA14 ( ortholog_one2one ) Mouse_ Car14 ( ortholog_one2one ) Pig_ CA14 ( ortholog_one2one ) Rat_ Ca14 ( ortholog_one2one ) Rabbit_ CA14 ( ortholog_one2one ) |
| Ohnologs | CA12, CA9 |
| Paralogs | CA9, CA5B, CA1, CA8, CA2, CA12, CA7, CA3, CA13, CA4, CA5A, CA6, CA11, CA10 |
| Tissue | NA |
| Tissue Specificity | High expression in all parts of the central nervous system and lower expression in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4LU3 (X-ray 2.00A ) 5CJF (X-ray 1.83A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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