| Gene Information | |
|---|---|
| Gene Name | GRIA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 902 |
| Protein Names | Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4) |
| Target Name | glutamate receptor ampa 4 |
| Target Type | Successful target |
| Gene Age | 886 ( ENSG00000152578 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P48058 |
| Gene Card | GRIA4 |
| Uniprot ID | P48058 |
| Pfam | PF01094; PF00060; PF10613 |
| In ASD | yes |
| Allosteric Prediction | yes (1.367032318) |
| Ortholog in Animals | Alpaca_ GRIA4 ( ortholog_one2one ) Dog_ GRIA4 ( ortholog_one2one ) GuineaPig_ GRIA4 ( ortholog_one2one ) Macaque_ GRIA4 ( ortholog_one2one ) Mouse_ Gria4 ( ortholog_one2one ) Pig_ GRIA4 ( ortholog_one2one ) Rat_ Gria4 ( ortholog_one2one ) Rabbit_ GRIA4 ( ortholog_one2one ) |
| Ohnologs | GRIA3, GRIA2, GRIA1 |
| Paralogs | GRIN3A, GRIN2A, GRIK5, GRIN2C, GRID1, GRID2, GRIK3, GRIN2D, GRIN1, GRIK4, GRIA3, GRIK1, GRIA2, GRIA1, GRIN3B, GRIK2, GRIN2B |
| Tissue | brain, cerebral.cortex, cerebellar.hemisphere, cerebellum |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1555050158 rs1555050165 rs1555050171 rs1555050174 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Interaction with CNIH2, CNIH3 and PRKCG promotes cell surface expression. {ECO:0000250}. |
| Mouse PG classification | NA |
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