| Gene Information | |
|---|---|
| Gene Name | HAUS8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 410 |
| Protein Names | HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000131351 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BT25 |
| Gene Card | HAUS8 |
| Uniprot ID | Q9BT25 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.279103811) |
| Ortholog in Animals | Alpaca_ HAUS8 ( ortholog_one2one ) Dog_ HAUS8 ( ortholog_one2one ) GuineaPig_ HAUS8 ( ortholog_one2one ) Macaque_ HAUS8 ( ortholog_one2one ) Mouse_ Haus8 ( ortholog_one2one ) Pig_ HAUS8 ( ortholog_one2one ) Rat_ Haus8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.22(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1130222 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217, ECO:0000269|PubMed:30723163}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000305|PubMed:19369198}. Note=During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively. Localizes to mitotic spindle microtubules. {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217, ECO:0000269|PubMed:30723163}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |