| Gene Information | |
|---|---|
| Gene Name | GRAMD1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 738 |
| Protein Names | Protein Aster-B (GRAM domain-containing protein 1B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000023171 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q3KR37 |
| Gene Card | GRAMD1B |
| Uniprot ID | Q3KR37 |
| Pfam | PF02893; PF16016 |
| In ASD | no |
| Allosteric Prediction | no (-1.55375635) |
| Ortholog in Animals | Alpaca_ GRAMD1B ( ortholog_one2one ) Dog_ GRAMD1B ( ortholog_one2one ) GuineaPig_ GRAMD1B ( ortholog_one2one ) Macaque_ GRAMD1B ( ortholog_one2one ) Mouse_ Gramd1b ( ortholog_one2one ) Pig_ GRAMD1B ( ortholog_one2one ) Rat_ Gramd1b ( ortholog_one2one ) Rabbit_ GRAMD1B ( ortholog_one2one ) |
| Ohnologs | GRAMD1A, GRAMD1C |
| Paralogs | GRAMD1A, GRAMD1C, GRAMD2A, GRAMD2B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:30220461}; Single-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:30220461}; Single-pass membrane protein {ECO:0000255}. Note=In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS). {ECO:0000269|PubMed:30220461}. |
| Mouse PG classification | NA |
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