| Gene Information | |
|---|---|
| Gene Name | RIT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 219 |
| Protein Names | GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000143622 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92963 |
| Gene Card | RIT1 |
| Uniprot ID | Q92963 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | yes (0.085279816) |
| Ortholog in Animals | Alpaca_ RIT1 ( ortholog_one2one ) Dog_ RIT1 ( ortholog_one2one ) GuineaPig_ RIT1 ( ortholog_one2one ) Macaque_ RIT1 ( ortholog_one2one ) Mouse_ Rit1 ( ortholog_one2one ) Pig_ RIT1 ( ortholog_one2one ) Rat_ Rit1 ( ortholog_one2one ) Rabbit_ RIT1 ( ortholog_one2one ) |
| Ohnologs | RIT2 |
| Paralogs | RRAS, RHEB, KRAS, DIRAS1, RRAS2, RAP2B, HRAS, RERG, RASL12, RRAD, DIRAS2, ERAS, NKIRAS1, RALB, RASD2, GEM, DIRAS3, MRAS, RAP2A, RASD1, REM1, NKIRAS2, RALA, RAP1A, RASL11B, RAP1B, RASL10A, RASL11A, REM2, RERGL, RIT2, RHEBL1, NRAS, RAP2C, RASL10B |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4KLZ (X-ray 2.30A ) |
| DBSNP | rs869025189 rs672601334 rs869025193 rs730881014 rs869025194 rs869025195 rs869025197 rs483352822 rs672601335 |
| Subcellular location [CC] | Cell membrane. |
| Mouse PG classification | NA |
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