| Gene Information | |
|---|---|
| Gene Name | MOGAT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 334 |
| Protein Names | 2-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2) (MGAT2) (hMGAT2) (Diacylglycerol O-acyltransferase candidate 5) (hDC5) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000166391 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q3SYC2 |
| Gene Card | MOGAT2 |
| Uniprot ID | Q3SYC2 |
| Pfam | PF03982 |
| In ASD | no |
| Allosteric Prediction | no (-0.640197831) |
| Ortholog in Animals | Alpaca_ MOGAT2 ( ortholog_one2one ) Dog_ MOGAT2 ( ortholog_one2one ) GuineaPig_ MOGAT2 ( ortholog_one2one ) Macaque_ MOGAT2 ( ortholog_one2one ) Mouse_ Mogat2 ( ortholog_one2one ) Rat_ Mogat2 ( ortholog_one2one ) Rabbit_ MOGAT2 ( ortholog_one2one ) |
| Ohnologs | AWAT2, DGAT2L6, AWAT1, MOGAT1 |
| Paralogs | MOGAT1, AWAT2, AWAT1, DGAT2L6, MOGAT3, DGAT2 |
| Tissue | duodenum, liver, small.intestine, colon, small.intestine.Peyers.patch, transverse.colon |
| Tissue Specificity | Highly expressed in liver, small intestine, colon, stomach and kidney. {ECO:0000269|PubMed:12621063, ECO:0000269|PubMed:12824082}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs554202 rs34582952 rs12281468 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12621063, ECO:0000269|PubMed:27184406}; Multi-pass membrane protein {ECO:0000269|PubMed:12621063}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:27184406}. |
| Mouse PG classification | NA |
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