| Gene Information | |
|---|---|
| Gene Name | GPT |
| Organism | Homo sapiens (Human) |
| Gene Length | 496 |
| Protein Names | Alanine aminotransferase 1 (ALT1) (EC 2.6.1.2) (Glutamate pyruvate transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1) (Glutamic--pyruvic transaminase 1) |
| Target Name | alanine aminotransferase 1 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000167701 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P24298 |
| Gene Card | GPT |
| Uniprot ID | P24298 |
| Pfam | PF00155 |
| In ASD | no |
| Allosteric Prediction | yes (0.750811617) |
| Ortholog in Animals | Alpaca_ GPT ( ortholog_one2one ) Dog_ GPT ( ortholog_one2one ) GuineaPig_ GPT ( ortholog_one2one ) Macaque_ GPT ( ortholog_one2one ) Mouse_ Gpt ( ortholog_one2one ) Rat_ Gpt ( ortholog_one2one ) |
| Ohnologs | GPT2 |
| Paralogs | ACCS, AADAT, KYAT3, TAT, GPT2, KYAT1, ACCSL |
| Tissue | NA |
| Tissue Specificity | Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue. {ECO:0000269|PubMed:11863375}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.023367(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1063739 rs141505249 rs147998249 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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