| Gene Information | |
|---|---|
| Gene Name | GPRK7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 465 |
| Protein Names | MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9HBH9 |
| Gene Card | MKNK2 |
| Uniprot ID | Q9HBH9 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed in all tissues examined. Isoform 2 is expressed at higher levels in the ovary than is isoform 1. {ECO:0000269|PubMed:11013076}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2AC3 (X-ray 2.10A ) 2AC5 (X-ray 3.20A ) 2HW7 (X-ray 2.71A ) 6CJ5 (X-ray 2.80A ) 6CJE (X-ray 3.36A ) 6CJH (X-ray 3.60A ) 6CJW (X-ray 3.38A ) 6CJY (X-ray 3.05A ) 6CK3 (X-ray 2.90A ) 6CK6 (X-ray 3.32A ) 6CKI (X-ray 2.95A ) 6JLR (X-ray 2.90A ) |
| DBSNP | rs3746101 rs56158214 rs34475638 |
| Subcellular location [CC] | [Isoform 2]: Nucleus, PML body.; [Isoform 1]: Cytoplasm. |
| Mouse PG classification | NA |
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