Gene Information
Gene NameGPRIN1
OrganismHomo sapiens (Human)
Gene Length1008
Protein NamesG protein-regulated inducer of neurite outgrowth 1 (GRIN1)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000169258 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ7Z2K8
Gene CardGPRIN1
Uniprot IDQ7Z2K8
PfamPF15235
In ASDno
Allosteric Predictionno (-1.0581145)
Ortholog in AnimalsDog_ GPRIN1 ( ortholog_one2one )
GuineaPig_ GPRIN1 ( ortholog_one2one )
Macaque_ GPRIN1 ( ortholog_one2one )
Mouse_ Gprin1 ( ortholog_one2one )
Pig_ GPRIN1 ( ortholog_one2one )
Rat_ Gprin1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissuebrain, cerebral.cortex, amygdala, cerebellar.hemisphere, cerebellum, hippocampus, hypothalamus, pituitary.gland
Tissue SpecificityWidely expressed in the central nervous system, with highest levels in spinal cord. {ECO:0000269|PubMed:10480904}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17854765  rs6556276  rs10037225  rs34285890 
Subcellular location [CC]Cell membrane {ECO:0000250};
Lipid-anchor {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Note=Highly enriched in growth cone. {ECO:0000250}.
Mouse PG classificationNA
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