| Gene Information | |
|---|---|
| Gene Name | GPRC5C |
| Organism | Homo sapiens (Human) |
| Gene Length | 441 |
| Protein Names | G-protein coupled receptor family C group 5 member C (Retinoic acid-induced gene 3 protein) (RAIG-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000170412 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NQ84 |
| Gene Card | GPRC5C |
| Uniprot ID | Q9NQ84 |
| Pfam | PF00003 |
| In ASD | yes |
| Allosteric Prediction | yes (0.52183277) |
| Ortholog in Animals | Alpaca_ GPRC5C ( ortholog_one2one ) Dog_ GPRC5C ( ortholog_one2one ) GuineaPig_ GPRC5C ( ortholog_one2one ) Macaque_ GPRC5C ( ortholog_one2one ) Mouse_ Gprc5c ( ortholog_one2one ) Pig_ GPRC5C ( ortholog_one2one ) Rat_ Gprc5c ( ortholog_one2one ) Rabbit_ GPRC5C ( ortholog_one2one ) |
| Ohnologs | GPRC5B |
| Paralogs | GPRC5B, GPRC5D, GPRC5A |
| Tissue | NA |
| Tissue Specificity | Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG). {ECO:0000269|PubMed:10945465, ECO:0000269|PubMed:11311935}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles. |
| Mouse PG classification | NA |
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