| Gene Information | |
|---|---|
| Gene Name | GPRC1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 872 |
| Protein Names | Metabotropic glutamate receptor 2 (mGluR2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14416 |
| Gene Card | GRM2 |
| Uniprot ID | Q14416 |
| Pfam | PF00003; PF01094; PF07562 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain. {ECO:0000269|PubMed:18297054}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4XAQ (X-ray 2.21A ) 4XAS (X-ray 2.35A ) 5CNI (X-ray 2.69A ) 5CNJ (X-ray 2.65A ) 5KZN (X-ray 2.80A ) 5KZQ (X-ray 2.80A ) 7E9G (EM 3.50A ) 7EPA (EM 3.60A ) 7EPB (EM 3.10A ) 7EPD (EM 3.90A ) 7MTQ (EM 3.65A ) 7MTR (EM 3.30A ) 7MTS (EM 3.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Synapse {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. |
| Mouse PG classification | NA |
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